{"id":353215,"date":"2016-04-04T10:46:59","date_gmt":"2016-04-04T15:46:59","guid":{"rendered":"https:\/\/content.findlaw-admin.com\/ability-law\/injury\/product-liability\/byetta-side-effects-faqs.html"},"modified":"2025-09-23T13:45:00","modified_gmt":"2025-09-23T18:45:00","slug":"byetta-side-effects-faqs","status":"publish","type":"page","link":"https:\/\/www.findlaw.com\/injury\/product-liability\/byetta-side-effects-faqs.html","title":{"rendered":"Byetta: Side Effects and FAQ"},"content":{"rendered":"\n<div class=\"wp-container-core-columns-is-layout-9d6595d7 fl-sectionWithSidebar fl-container fl-flex fl-flex-wrap fl-gap30\">\n<div class=\"fl-page-articles fl-section-main fl-section-main-full-width\"><h1 class=\"fl-no-margin-top\">Byetta: Side Effects and FAQ<\/h1>\n\n<section class=\"fl-gutenberg-byline\">\n    <div class=\"fl-gutenberg-byline-content\">\n                    By <a href=\"https:\/\/www.findlaw.com\/company\/our-team\/christie-nicholson-j-d\/\">Christie Nicholson, J.D.<\/a> | Legally reviewed by <a\n                href=\"https:\/\/www.findlaw.com\/company\/our-team\/oni-harton-j-d\/\">Oni Harton, J.D.<\/a>\n                | Last updated\n        <time>\n                            September 23, 2025\n                    <\/time>\n    <\/div>\n\n    \n    <details class=\"fl-gutenberg-byline-toggle fl-gutenberg-byline-legally-reviewed\">\n        <summary>\n            <i class=\"fl-gutenberg-byline-icon\" aria-hidden=\"true\"><\/i>\n            Legally Reviewed\n        <\/summary>\n\n        <div class=\"fl-gutenberg-byline-toggle-content\">\n            <p><em>This article has been written and reviewed for legal accuracy, clarity, and style by <a href=\"https:\/\/www.findlaw.com\/company\/our-team.html\">FindLaw\u2019s team of legal writers and attorneys<\/a> and in accordance with <a href=\"https:\/\/www.findlaw.com\/company\/company-history\/editorial-policy.html\">our editorial standards<\/a>.<\/em><\/p>\n\n        <\/div>\n    <\/details>\n\n    <details class=\"fl-gutenberg-byline-toggle fl-gutenberg-byline-fast-checked\">\n        <summary>\n            <i class=\"fl-gutenberg-byline-icon\" aria-hidden=\"true\"><\/i>\n            Fact-Checked\n        <\/summary>\n\n        <div class=\"fl-gutenberg-byline-toggle-content\">\n            <p><em>The last updated date refers to the last time this article was reviewed by FindLaw or one of our <a href=\"https:\/\/www.findlaw.com\/company\/our-team\/contributing-authors.html\">contributing authors<\/a>. We make every effort to keep our articles updated. For information regarding a specific legal issue affecting you, please <a href=\"https:\/\/lawyers.findlaw.com\/?fli=bylinelink\" target=\"_blank\" rel=\"noopener\">contact an attorney in your area<\/a>.<\/em><\/p>\n\n        <\/div>\n    <\/details>\n<\/section>\n\n\n\n<p>Byetta is a medication used to treat type-2 diabetes. Byetta is a <a href=\"https:\/\/www.webmd.com\/obesity\/weight-loss-prescription-weight-loss-medicine\" target=\"_blank\" rel=\"noopener\">glucagon-like peptide 1<\/a> (GLP-1) that acts on the brain to reduce appetite and regulate blood glucose levels. This drug comes in a prefilled pen. It is an injectable drug, with most patients using their Byetta pen twice daily.<\/p>\n<p><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/326676\" target=\"_blank\" rel=\"noopener\">Byetta<\/a>\u00a0has worked to both control blood sugar levels and trigger weight loss. However, many patients have reported both mild and severe side effects. Studies have also linked the long-acting version of the drug to various forms of cancer, including thyroid cancer. As a result, thousands of patients have filed lawsuits against the drug&#8217;s manufacturer, AstraZeneca.<\/p>\n<p>This section answers common questions about Byetta and its side effects. If you have questions or concerns about Byetta, contact your healthcare provider.<\/p>\n<p>Drug manufacturers have a legal duty to ensure their medications carry adequate warnings and are safe to use. If you have been harmed by Byetta or another drug, you may have a legal claim. Contact a <a href=\"https:\/\/lawyers.findlaw.com\/products-liability-law\/\" target=\"_blank\" rel=\"noopener\">product liability attorney<\/a> near you to share your story and learn how to best pursue compensation for your injuries.<\/p>\n<h2>What is Byetta?<\/h2>\n<p>Byetta (Exenatide) is a\u00a0<a href=\"http:\/\/www.nlm.nih.gov\/medlineplus\/druginfo\/meds\/a605034.html\" target=\"_blank\" rel=\"noopener\">diabetes drug<\/a>. Patients taking Byetta inject it twice daily to help their body metabolize blood sugar (glucose). High blood sugar is the main characteristic of diabetes, and medications such as Byetta promise to help patients manage their blood sugar levels.<\/p>\n<p>Byetta belongs to a class of similar diabetes drugs called incretin mimetics. AstraZeneca produced and sold Byetta from 2014 until it <a href=\"https:\/\/www.uhcprovider.com\/en\/resource-library\/news\/2024\/discontinuation-bydureon-bcise-byetta.html\" target=\"_blank\" rel=\"noopener\">discontinued the drug<\/a> in October 2024 for business reasons.<\/p>\n<p>Many patients take Byetta and other medications like metformin to help control their diabetes.<\/p>\n<h2>How does Byetta treat diabetes?<\/h2>\n<p>Most diabetics manage their blood sugar levels through diet, exercise, and insulin injections. When these measures prove insufficient, doctors may prescribe Byetta for patients with\u00a0<a href=\"http:\/\/www.diabetes.org\/diabetes-basics\/type-2\/\" target=\"_blank\" rel=\"noopener\">type 2 diabetes<\/a>.<\/p>\n<p>Byetta and other incretin mimetic drugs treat diabetes by focusing on the pancreas&#8217;s production of insulin and <a href=\"https:\/\/www.webmd.com\/diabetes\/glucagon-blood-sugar\" target=\"_blank\" rel=\"noopener\">glucagon<\/a>.<\/p>\n<p>Byetta is a receptor agonist. This means it works on the brain to convince a person&#8217;s body that they aren&#8217;t hungry. It also makes the person feel fuller for longer and helps reduce their appetite and\u00a0their cravings for foods high in sugar.<\/p>\n<h2>What should I know about Byetta?<\/h2>\n<p>Patients <a href=\"https:\/\/www.webmd.com\/drugs\/2\/drug-93242\/byetta-subcutaneous\/details\" target=\"_blank\" rel=\"noopener\">using Byetta<\/a> should know:<\/p>\n<ul>\n<li>The FDA only approved Byetta for patients diagnosed with type 2 diabetes. The FDA does not recommend this drug for patients with type 1 diabetes.<\/li>\n<li>Byetta is not a substitute for insulin.<\/li>\n<li>Byetta is supposed to complement your diet and exercise regimen. No diabetes medication can be a substitute for a healthy diet and regular exercise.<\/li>\n<li>Many patients lose weight after starting Byetta. For many people, this is a positive side effect. However, significant weight loss can also indicate something is wrong.<\/li>\n<\/ul>\n<p>You must see your healthcare professional often to ensure that you are okay when using any medication.<\/p>\n<h2>What are the mild side effects of Byetta?<\/h2>\n<p>As with most other drugs, Byetta does have common side effects. These can be relatively minor problems or potentially serious. Minor side effects can include,\u00a0but are not limited to,\u00a0the following:<\/p>\n<ul>\n<li>Nausea<\/li>\n<li>Vomiting<\/li>\n<li>Diarrhea<\/li>\n<li>Loss of appetite<\/li>\n<li>Indigestion<\/li>\n<li>Headaches<\/li>\n<li>Fast heartbeat<\/li>\n<li>Injection-site reactions<\/li>\n<li>Dizziness<\/li>\n<li>Confusion<\/li>\n<li>Chills<\/li>\n<li>Drowsiness<\/li>\n<li>Lightheadedness<\/li>\n<li>Bloating<\/li>\n<li>Excessive weight loss<\/li>\n<\/ul>\n<p>There is no evidence that Byetta affects your blood pressure. However, if you notice a significant change in your blood pressure or symptoms of low blood sugar, call your primary healthcare provider immediately.<\/p>\n<h2>Are there more serious side effects of Byetta?<\/h2>\n<p>One reason so many patients have sued AstraZeneca is that Byetta can cause\u00a0severe side effects. Some serious Byetta side effects can be life-threatening. For example, several patients reported developing <a href=\"https:\/\/www.webmd.com\/digestive-disorders\/digestive-diseases-pancreatitis\" target=\"_blank\" rel=\"noopener\">pancreatitis<\/a> and <a href=\"https:\/\/www.webmd.com\/cancer\/pancreatic-cancer\/digestive-diseases-pancreatic-cancer\" target=\"_blank\" rel=\"noopener\">pancreatic cance<\/a>r after taking Byetta.<\/p>\n<p>Other serious side effects include the following:<\/p>\n<ul>\n<li>Feeling jittery<\/li>\n<li>Constipation<\/li>\n<li>Low blood sugar<\/li>\n<li>Hypoglycemia<\/li>\n<li>Kidney problems<\/li>\n<li>Issues with kidney function<\/li>\n<\/ul>\n<p>There is no evidence that Byetta affects your blood pressure. However, if you notice a significant change in your blood pressure or symptoms of low blood sugar, call your primary healthcare provider immediately.<\/p>\n<p>Numerous studies have found an association between the drug and pancreas ailments. There&#8217;s also concern that Byetta is associated with an increased risk of <a href=\"https:\/\/www.webmd.com\/cancer\/what-is-thyroid-cancer\" target=\"_blank\" rel=\"noopener\">thyroid cancer<\/a>.<\/p>\n<h2>What happens if you&#8217;re allergic to Byetta?<\/h2>\n<p>One risk of taking a new prescription drug is that you may have an allergic reaction. Your doctor will check for any adverse drug interactions. They&#8217;ll also do their best to anticipate any allergies.<\/p>\n<p>You should also review the <a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2014\/021773s036lbl.pdf\" target=\"_blank\" rel=\"noopener\">medication guide<\/a> and any prescribing information to see if you may be allergic. People who are allergic to Byetta experience additional side effects, including:<\/p>\n<ul>\n<li>Hives<\/li>\n<li>Rash or skin irritation<\/li>\n<li>Swelling of the tongue, mouth, and throat<\/li>\n<li>Trouble breathing<\/li>\n<li>Chest tightening<\/li>\n<\/ul>\n<p>You must see your doctor immediately if you notice any of these symptoms. If this isn&#8217;t possible, go to the emergency room.<\/p>\n<h2>Does Byetta increase the risk of pancreatitis?<\/h2>\n<p>Multiple studies and post-marketing reports have found that Byetta can\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23440284\" target=\"_blank\" rel=\"noopener\">increase a patient&#8217;s risk of pancreatitis<\/a>. Pancreatitis is the inflammation of the pancreas. It can lead to worsened diabetes, kidney failure, infection, and even death. The\u00a0<a href=\"http:\/\/www.mayoclinic.org\/diseases-conditions\/pancreatitis\/basics\/symptoms\/con-20028421\" target=\"_blank\" rel=\"noopener\">chief symptoms of acute pancreatitis<\/a>\u00a0include upper abdominal pain, nausea, vomiting, and unexplained weight loss.<\/p>\n<p>The U.S. Food and Drug Administration (FDA) has issued several warnings about this risk. In October 2007, the FDA advised doctors not to prescribe Byetta to patients with pancreatitis. You will find more alerts on\u00a0<a href=\"http:\/\/www.fda.gov\/Drugs\/DrugSafety\/PostmarketDrugSafetyInformationforPatientsandProviders\/ucm113705.htm\" target=\"_blank\" rel=\"noopener\">Byetta&#8217;s FDA postmarket drug safety page<\/a>.<\/p>\n<h2>Does Byetta increase the risk of pancreatic cancer?<\/h2>\n<p>There&#8217;s a growing debate over whether Byetta increases the risk of pancreatic cancer. The medical community remains divided on the subject. Some studies have found that these drugs\u00a0<a href=\"http:\/\/care.diabetesjournals.org\/content\/33\/2\/453.full\" target=\"_blank\" rel=\"noopener\">increase the risk of developing pancreatic cancer<\/a>. Other studies have\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22845701\" target=\"_blank\" rel=\"noopener\">found that they do not<\/a>.<\/p>\n<p>However, the seriousness of this concern has drawn attention. It has also caused thousands of patients to sue the drug manufacturer. Some patients who claim to have developed pancreatic cancer after taking Byetta have\u00a0<a href=\"https:\/\/www.findlaw.com\/injury\/product-liability\/byetta-lawsuit-information.html\">sued the drug&#8217;s manufacturer<\/a>.<\/p>\n<h2>Does Byetta cause other forms of cancer?<\/h2>\n<p>The long-acting version of Byetta has warnings for\u00a0thyroid cancer. To date, none of the clinical trials have involved humans. However, in the studies that do exist, researchers found that Byetta caused\u00a0tumors in the thyroid. Evidence shows that drugs similar to Byetta may cause thyroid cancer.<\/p>\n<p>Some of these\u00a0<a href=\"https:\/\/www.medicalnewstoday.com\/articles\/drugs-byetta-side-effects#fa-qs\" target=\"_blank\" rel=\"noopener\">drugs include<\/a>\u00a0the following:<\/p>\n<ul>\n<li>Dulaglutide (Trulicity)<\/li>\n<li>Liraglutide (Victoza)<\/li>\n<li>Semaglutide (Ozempic, Wegovy)<\/li>\n<li>Long-acting Exenatide (Byetta) Bydureon Bcise<\/li>\n<\/ul>\n<p>See your doctor immediately if you&#8217;ve taken Byetta or any other drug and developed thyroid cancer. You may also need to talk to a product liability attorney. You may have a legal claim for damages.<\/p>\n<h2>Does Byetta affect the gallbladder?<\/h2>\n<p>Studies have shown that Byetta may cause gallbladder issues, from gallstones to cholecystitis (inflammation). Of course, there is ample evidence\u00a0<a href=\"https:\/\/www.everydayhealth.com\/gallbladder\/symptoms\/link-between-gallstones-obesity-weight-loss\/\" target=\"_blank\" rel=\"noopener\">linking obesity to gallbladder problems<\/a>. Since obesity can cause issues with\u00a0<a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/obesity\/symptoms-causes\/syc-20375742#:~:text=Obesity%20makes%20you%20more%20likely%20to%20have%20high,raises%20the%20risk%20of%20insulin%20resistance%20and%20diabetes.\" target=\"_blank\" rel=\"noopener\">type-2 diabetes<\/a>, there&#8217;s a chance that your gallbladder stones or inflammation may related to something other than Byetta.<\/p>\n<p>Your attorney must prove that your health issues were caused by\u00a0the drug and\u00a0not other factors, such as personal diet, physical health, and lifestyle.<\/p>\n<h2>Is Byetta safe for pregnancy and breastfeeding?<\/h2>\n<p>Pregnant and nursing women must be careful about any medications they take. While there have not been any studies of the effects of Byetta on humans, there have been plenty of\u00a0<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2015\/021773s040lbl.pdf\" target=\"_blank\" rel=\"noopener\">studies on animals<\/a>.<\/p>\n<p>According to these studies, Byetta did cause fetal harm in animals. Some of the issues caused by the drug include:<\/p>\n<ul>\n<li>Cleft palate<\/li>\n<li>Neonatal death<\/li>\n<li>Irregular skeletal ossification<\/li>\n<\/ul>\n<p>The FDA created a registry where pregnant women can report any complications they experienced after taking Byetta while pregnant or nursing. If you are pregnant and wish to register, visit their\u00a0<a href=\"https:\/\/www.fda.gov\/science-research\/womens-health-research\/pregnancy-exposure-registries\" target=\"_blank\" rel=\"noopener\">Pregnant Registries<\/a>\u00a0site.<\/p>\n<h2>Can I use Byetta for weight loss?<\/h2>\n<p>Some people have been using similar Type-2 diabetes medications to lose weight and wonder if they can use Byetta as well. For example, many people without diabetes, especially celebrities, have taken <a href=\"https:\/\/www.webmd.com\/drugs\/2\/drug-174491\/ozempic-subcutaneous\/details\" target=\"_blank\" rel=\"noopener\">Ozempic<\/a> for rapid weight loss.<\/p>\n<p>Byetta poses health risks and severe side effects that may outweigh the benefits of losing weight. Furthermore, not all diabetes patients experience weight loss. The FDA has not approved Byetta for weight loss. That is a possible side effect of the medication. Simply put, Byetta cannot replace a healthy diet and exercise.<\/p>\n<h2>Has AstraZeneca recalled Byetta?<\/h2>\n<p>To date, neither the FDA nor AstraZeneca have recalled Byetta. However, hundreds of patients have <a href=\"https:\/\/www.findlaw.com\/injury\/product-liability\/pharmaceutical-drug-liability.html\">sued the drug manufacturer<\/a>, alleging that the medication causes pancreatitis, pancreatic cancer, thyroid cancer, and kidney failure.<\/p>\n<p>AstraZeneca discontinued Byetta for business reasons in October 2024.<\/p>\n<h2>I Experienced Adverse Health Effects After Taking Byetta. What Should I Do?<\/h2>\n<p>Contact your doctor immediately if you took or are taking Byetta and have developed adverse health reactions. For patients who have suffered severe injuries, consider contacting an attorney to discuss your legal options.<\/p>\n<p>FindLaw&#8217;s directory of <a href=\"https:\/\/lawyers.findlaw.com\/products-liability-law\/\" target=\"_blank\" rel=\"noopener\">product liability attorneys<\/a> can get you started. Select your state or city to review contact and ratings information for local experts. 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Injury Lawyers<\/a><\/li>\n                            <\/ul>\n        <\/div>\n    <\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Byetta has been linked to serious risks like pancreatitis and pancreatic and thyroid cancers. Learn about drug manufacturer liability and more at FindLaw.<\/p>\n","protected":false},"author":41135,"featured_media":0,"parent":353191,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"app\/Http\/Controllers\/Templates\/ArticleWithBreadcrumbsController.php","meta":{"_acf_changed":false,"_stopmodifiedupdate":true,"_modified_date":"","_autodraft_ids":[],"_cloudinary_featured_overwrite":false,"_sb_is_suggestion_mode":false,"_sb_show_suggestion_boards":false,"_sb_show_comment_boards":false,"_sb_suggestion_history":"","_sb_update_block_changes":"","_is_real_time_mode":false,"_realtime_collaborators":"","footnotes":"","cf_checklist_status":[]},"categories":[2734],"tags":[],"state_laws_tags":[],"flmsa":[],"class_list":["post-353215","page","type-page","status-publish","hentry","category-injury"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/pages\/353215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/users\/41135"}],"replies":[{"embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/comments?post=353215"}],"version-history":[{"count":0,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/pages\/353215\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/pages\/353191"}],"wp:attachment":[{"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/media?parent=353215"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/categories?post=353215"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/tags?post=353215"},{"taxonomy":"state_laws_tags","embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/state_laws_tags?post=353215"},{"taxonomy":"flmsa","embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/flmsa?post=353215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}