{"id":353336,"date":"2016-09-02T17:01:08","date_gmt":"2016-09-02T22:01:08","guid":{"rendered":"https:\/\/content.findlaw-admin.com\/ability-law\/injury\/product-liability\/prevacid-prilosec-and-nexium-lawsuits.html"},"modified":"2025-07-31T11:01:54","modified_gmt":"2025-07-31T16:01:54","slug":"prevacid-prilosec-and-nexium-lawsuits","status":"publish","type":"page","link":"https:\/\/www.findlaw.com\/injury\/product-liability\/prevacid-prilosec-and-nexium-lawsuits.html","title":{"rendered":"Prevacid, Prilosec, and Nexium Lawsuits"},"content":{"rendered":"\n<div class=\"wp-container-core-columns-is-layout-9d6595d7 fl-sectionWithSidebar fl-container fl-flex fl-flex-wrap fl-gap30\">\n<div class=\"fl-page-articles fl-section-main fl-section-main-full-width\"><h1 class=\"fl-no-margin-top\">Proton Pump Inhibitors (PPI) Lawsuits: Prevacid, Prilosec and Nexium<\/h1>\n\n<section class=\"fl-gutenberg-byline\">\n    <div class=\"fl-gutenberg-byline-content\">\n                    By <a href=\"https:\/\/www.findlaw.com\/company\/our-team\/natalie-moritz\/\">Natalie Moritz<\/a> | Legally reviewed by <a\n                href=\"https:\/\/www.findlaw.com\/company\/our-team\/jordan-walker-j-d\/\">Jordan Walker, J.D.<\/a>\n                | Last reviewed\n        <time>\n                            July 31, 2025\n                    <\/time>\n    <\/div>\n\n    \n    <details class=\"fl-gutenberg-byline-toggle fl-gutenberg-byline-legally-reviewed\">\n        <summary>\n            <i class=\"fl-gutenberg-byline-icon\" aria-hidden=\"true\"><\/i>\n            Legally Reviewed\n        <\/summary>\n\n        <div class=\"fl-gutenberg-byline-toggle-content\">\n            <p><em>This article has been written and reviewed for legal accuracy, clarity, and style by <a href=\"https:\/\/www.findlaw.com\/company\/our-team.html\">FindLaw\u2019s team of legal writers and attorneys<\/a> and in accordance with <a href=\"https:\/\/www.findlaw.com\/company\/company-history\/editorial-policy.html\">our editorial standards<\/a>.<\/em><\/p>\n\n        <\/div>\n    <\/details>\n\n    <details class=\"fl-gutenberg-byline-toggle fl-gutenberg-byline-fast-checked\">\n        <summary>\n            <i class=\"fl-gutenberg-byline-icon\" aria-hidden=\"true\"><\/i>\n            Fact-Checked\n        <\/summary>\n\n        <div class=\"fl-gutenberg-byline-toggle-content\">\n            <p><em>The last updated date refers to the last time this article was reviewed by FindLaw or one of our <a href=\"https:\/\/www.findlaw.com\/company\/our-team\/contributing-authors.html\">contributing authors<\/a>. We make every effort to keep our articles updated. For information regarding a specific legal issue affecting you, please <a href=\"https:\/\/lawyers.findlaw.com\/?fli=bylinelink\" target=\"_blank\" rel=\"noopener\">contact an attorney in your area<\/a>.<\/em><\/p>\n\n        <\/div>\n    <\/details>\n<\/section>\n\n\n    <div class=\"fl-callout-text article-blockquote\">\n        <p>Studies have linked long-term heartburn drug use to increased risks of kidney failure, cognitive decline, and other serious health issues. Under product liability laws, consumers have filed lawsuits against the makers of Prevacid, Prilosec, and Nexium, alleging that these drugs caused serious health issues like chronic kidney disease and dementia.<\/p>\n\n    <\/div>\n\n\n\n<p>Consumers have filed a growing number of lawsuits against the manufacturers of proton pump inhibitors (PPIs),\u00a0a class of drugs commonly used to treat acid reflux and related conditions. Lawsuits claim that these heartburn medications may be linked to serious health conditions such as chronic kidney disease and dementia.<\/p>\n<p>This article provides an overview of lawsuits involving proton pump inhibitors. You&#8217;ll find information on alleged health risks,\u00a0<a href=\"https:\/\/www.findlaw.com\/injury\/product-liability\/pharmaceutical-drug-liability.html\">claims against drugmakers<\/a>, and your legal options. This article focuses on three specific heartburn drugs:<\/p>\n<ul>\n<li>Prevacid<\/li>\n<li>Prilosec<\/li>\n<li>Nexium<\/li>\n<\/ul>\n<p>If you&#8217;ve been diagnosed with chronic kidney disease, kidney failure, or dementia after regularly taking Prevacid, Prilosec, or Nexium, you may have a legal claim under product liability law. To understand your rights and legal options, contact a\u00a0<a href=\"https:\/\/lawyers.findlaw.com\/drugs-medical-devices\/?fli=dcta\" target=\"_blank\" rel=\"noopener\">personal injury attorney<\/a>\u00a0near you.<\/p>\n<h2>What Are Proton Pump Inhibitors (PPIs)?<\/h2>\n<p>The class of drugs\u00a0<a href=\"https:\/\/medlineplus.gov\/ency\/patientinstructions\/000381.htm\" target=\"_blank\" rel=\"noopener\">collectively referred to as PPIs<\/a>\u00a0works by reducing the amount of acid produced by the glands in the stomach lining, relieving the symptoms of acid reflux and heartburn. PPIs can treat gastric ulcers and gastroesophageal reflux disease (GERD). They can also be used with antibiotics to treat certain infections in the gut, like\u00a0<a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/21463-h-pylori-infection\" target=\"_blank\" rel=\"noopener\">helicobacter pylori<\/a>\u00a0(H. pylori).<\/p>\n<p>PPIs are available in either tablet or capsule form. They are meant to be taken in short intervals, usually no more than 14 days at a time.<\/p>\n<h2>PPI Brand Names, Generics, and Drug Manufacturers<\/h2>\n<p>There are several PPI drugs on the market. This article discusses:<\/p>\n<ul>\n<li>Prilosec, produced by\u00a0AstraZeneca\u00a0(generic omeprazole)<\/li>\n<li>Nexium,\u00a0produced by\u00a0AstraZeneca\u00a0(esomeprazole)<\/li>\n<li>Prevacid, produced by\u00a0Takeda Pharmaceuticals(lansoprazole)<\/li>\n<\/ul>\n<p>Prilosec, Prevacid, and Nexium are available over-the-counter (OTC). However, higher doses and certain\u00a0forms of these drugs may\u00a0require a prescription.<\/p>\n<p>AstraZeneca originally developed and marketed Prilosec as a prescription medication. After its patent expired, the manufacturer transitioned it to an OTC product. As part of this effort, AstraZeneca partnered with Procter &amp; Gamble to market and distribute Prilosec OTC in the United States. The U.S. Food &amp; Drug Administration (FDA)\u00a0<a href=\"https:\/\/www.fda.gov\/about-fda\/center-drug-evaluation-and-research-cder\/prilosec-otc-omeprazole-information\" target=\"_blank\" rel=\"noopener\">approved Prilosec OTC in 2003<\/a>.<\/p>\n<p>Other PPIs not discussed on this page include Dexilant (dexlansoprazole), Protonix (pantoprazole), and Aciphex (rabeprazole).<\/p>\n<h2>PPIs: Loss of Kidney Function and Other Serious Health Concerns<\/h2>\n<p>The most commonly cited medical study linking PPIs to\u00a0<a href=\"https:\/\/medlineplus.gov\/ency\/article\/000471.htm\" target=\"_blank\" rel=\"noopener\">chronic kidney disease<\/a>\u00a0(CKD) was published in the Journal of the American Medical Association (JAMA) in February 2016. The report, entitled &#8220;<a href=\"http:\/\/archinte.jamanetwork.com\/article.aspx?articleid=2481157\" target=\"_blank\" rel=\"noopener\">Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease<\/a>,&#8221; analyzed data from 10,482 participants over a 15-year period. It concluded that patients taking Nexium had a 20%\u00a0to 50%\u00a0higher risk of developing CKD than those given alternative treatments.<\/p>\n<p>One of the concerns about CDK is that it\u00a0worsens\u00a0over a period of months or even years, often without noticeable symptoms until the point of renal failure. At this point, called\u00a0<a href=\"https:\/\/medlineplus.gov\/ency\/article\/000500.htm\" target=\"_blank\" rel=\"noopener\">end-stage renal disease<\/a>\u00a0(ESRD), patients often\u00a0require dialysis or a transplant in order to survive.<\/p>\n<p>Another study published by JAMA in February 2016, entitled &#8220;<a href=\"http:\/\/archneur.jamanetwork.com\/article.aspx?articleid=2487379\" target=\"_blank\" rel=\"noopener\">Association of Proton Pump Inhibitors With Risk of Dementia<\/a>,&#8221; linked the long-term use of PPIs by seniors 75 and older to a 44% increased risk of dementia\u00a0when compared to those taking a placebo. However, the author of the study said more research is needed to make a definitive cause-and-effect conclusion.<\/p>\n<p>Less-severe side effects such as diarrhea and increased risk of bone fractures are listed on the U.S. Food and Drug Administration&#8217;s (FDA)\u00a0<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/021153s044,021957s014,022101s011mg.pdf\" target=\"_blank\" rel=\"noopener\">medication guide for Nexium<\/a>. Lawsuits allege that drugmaker AstraZeneca\u00a0<a href=\"https:\/\/www.findlaw.com\/injury\/product-liability\/defects-in-warnings.html\">failed to warn<\/a>\u00a0physicians and users about the drug&#8217;s more serious risks. Prilosec and\u00a0<a href=\"https:\/\/content.takeda.com\/?contenttype=PI&amp;product=PRVAC&amp;language=ENG&amp;country=GBL&amp;documentnumber=1\" target=\"_blank\" rel=\"noopener\">Prevacid<\/a>\u00a0have also been blamed for these injuries.<\/p>\n<p>Some other side effects of PPIs include:<\/p>\n<ul>\n<li>Headache and light-headedness<\/li>\n<li>Fever<\/li>\n<li>Abdominal pain, constipation, diarrhea, gas, nausea, and vomiting<\/li>\n<li>Low magnesium or vitamin B12<\/li>\n<li>Rash<\/li>\n<\/ul>\n<p>Other side effects are possible as well.<\/p>\n<h2>Proton Pump Inhibitor Lawsuits and Claims<\/h2>\n<p>If you have been injured by an OTC or prescription drug, one of your options is to file a personal injury lawsuit against the drugmaker.\u00a0<a href=\"https:\/\/www.findlaw.com\/injury\/product-liability\/pharmaceutical-drug-liability.html\">Pharmaceutical companies<\/a>\u00a0often are held liable for:<\/p>\n<ul>\n<li><a href=\"https:\/\/www.findlaw.com\/injury\/product-liability\/deceptive-marketing-of-drugs-and-the-failure-to-warn.html\">Failing to warn<\/a>\u00a0consumers about known risks\u00a0or risks they\u00a0<em data-redactor-tag=\"em\">should have<\/em>\u00a0known<\/li>\n<li>Negligence in the way the drug is tested or promoted<\/li>\n<li>Negligence in how the company responds to reports of serious side effects<\/li>\n<\/ul>\n<p>In some cases, the physician may be held\u00a0<a href=\"https:\/\/www.findlaw.com\/injury\/medical-malpractice\/can-i-sue-my-doctor.html\">liable for malpractice<\/a>\u00a0for improperly prescribing the drug.<\/p>\n<h3>Nexium and Prilosec Lawsuits (AstraZeneca)<\/h3>\n<p>AstraZeneca, which originally sold Prilosec along with Nexium, has been sued by several plaintiffs claiming that the company failed to provide necessary warnings about the risk of kidney damage when using its heartburn drugs.<\/p>\n<p>In 2024, AstraZeneca agreed to pay\u00a0<a href=\"https:\/\/ca.finance.yahoo.com\/news\/2-astrazeneca-pay-425-mln-062757999.html?guce_referrer=aHR0cHM6Ly93d3cuc2VsZWN0anVzdGljZS5jb20v&amp;guce_referrer_sig=AQAAAAS1FN6pYm32Gxcs1QzXvwk_sKZjP5UPoq6il28elwhTcgzqwV2SVFhqUq_PZpxInI7xqFZAnIyecdqSCO_WZNqtVX-sXhSJvc3pEBwZxltLcL6NzyZQWvyhnrJpdrRCVt_x2nV8QRb7-v_orKa0qSMCTYrLue9HB_-GPIifY52F\" target=\"_blank\" rel=\"noopener\">$425 million to settle thousands of U.S. lawsuits<\/a>\u00a0related to Nexium and Prilosec. The lawsuit settlements were part of a multidistrict litigation (MDL) centralized in New Jersey. This means each case was handled individually but coordinated for efficiency.<\/p>\n<p>One plaintiff, Charles Bowers, took the drug for roughly five years and developed a condition that led to kidney disease and eventually end-stage renal failure. In his 2016 complaint,\u00a0<a href=\"http:\/\/www.aboutlawsuits.com\/wp-content\/uploads\/2016-07-05-Bowers-Complaint.pdf\" target=\"_blank\" rel=\"noopener\">Bowers claimed\u00a0AstraZeneca was negligent<\/a>\u00a0in &#8220;the design, development, manufacture, testing, packaging, promoting, marketing, distribution, labeling, and\/or sale of the proton pump inhibiting drug known as Nexium.&#8221;<\/p>\n<p>Bowers claimed\u00a0he was forced to undergo\u00a0kidney dialysis treatments three times per week and\u00a0told he needed a kidney transplant. In addition to the costs related to the need for lifelong treatment, Bowers claimed\u00a0his condition has caused him mental anguish and\u00a0<a href=\"https:\/\/www.findlaw.com\/injury\/torts-and-personal-injuries\/emotional-distress.html\">emotional distress<\/a>.<\/p>\n<p>According to the complaint, Bowers&#8217; suit seeks\u00a0<a href=\"https:\/\/www.findlaw.com\/injury\/accident-injury-law\/injury-damages.html\">compensatory and actual damages<\/a>\u00a0of more than $75,000. Bowers also seeks punitive damages for allegedly marketing a dangerous drug to millions of U.S. users.<\/p>\n<p>Other lawsuits against PPI pharmaceuticals make similar claims. Thousands of these suits also involve Prevacid (Takeda Pharmaceutical) and Protonix (Pfizer).<\/p>\n<p>As thousands of similar claims emerged, the courts organized these cases into multidistrict litigation. To help determine the viability of these claims and guide future proceedings, representative cases,\u00a0known as bellwether trials,\u00a0were selected to test key legal arguments and evidence.<\/p>\n<h3>Bellwether Trials<\/h3>\n<p>In\u00a0<a href=\"https:\/\/www.findlaw.com\/injury\/torts-and-personal-injuries.html\">mass tort litigation<\/a>, a bellwether trial is a representative case selected from a larger group of lawsuits involving the same drug or medical product. These trials are used to test the strength of the plaintiffs&#8217; claims,\u00a0such as whether a drug caused serious side effects or whether the manufacturer failed to provide adequate warnings.<\/p>\n<p>The outcomes help both sides assess how juries might respond to the\u00a0<a href=\"https:\/\/www.findlaw.com\/hirealawyer\/choosing-the-right-lawyer\/evidence-law.html\">evidence and arguments<\/a>, and often influence settlement negotiations. In the context of PPI lawsuits, bellwether trials help streamline complex litigation involving thousands of patients harmed by the same drug.<\/p>\n<h3>Prevacid Lawsuits and Bone Fractures (Takeda Pharmaceuticals)<\/h3>\n<p>In 2014, Takeda Pharmaceutical agreed to settle lawsuits alleging that Prevacid was linked to an increased risk of bone fractures. While the company resolved the claims, the terms of the settlement,\u00a0including the total amount paid,\u00a0were not publicly disclosed.<\/p>\n<h2>Injured by a Proton Pump Inhibitor? Talk to an Attorney<\/h2>\n<p>When you take prescription or OTC medications, you trust that the drugs have been thoroughly tested and potential risks are clearly communicated. When pharmaceutical companies fail to meet these obligations, they may be held accountable under\u00a0<a href=\"https:\/\/www.findlaw.com\/injury\/product-liability\/what-is-product-liability.html\">product liability laws<\/a>. These are laws that allow\u00a0victims\u00a0to seek compensation for harm caused by defective or dangerous products.<\/p>\n<p>If you have been using Prevacid, Prilosec, or Nexium and have developed kidney problems, dementia, or other serious side effects,\u00a0your first priority should be\u00a0getting the medical care you need. After that, seeking relief for your injuries is the next logical step.<\/p>\n<p>You\u00a0may be able to recover for your injuries, including ongoing medical costs and the general suffering that accompanies these types of health problems. Contact an\u00a0<a href=\"https:\/\/lawyers.findlaw.com\/drugs-medical-devices\/?fli=dcta\" target=\"_blank\" rel=\"noopener\">injury lawyer<\/a>\u00a0with experience in product liability litigation for help. A skilled attorney can assess whether you have a valid claim for a PPI lawsuit and advise on next steps.<\/p>\n\n\n<div class=\"was-this-helpful\">\n    <div\n            class=\"was-this-helpful__question-container\"\n            aria-labelledby=\"was-this-helpful__question\"\n            role=\"group\"\n    >\n        <span\n                id=\"was-this-helpful__question\"\n                class=\"was-this-helpful__question fl-text-lg-bold\"\n        >Was this helpful?<\/span>\n        <button\n                class=\"was-this-helpful__button fl-text-sm\"\n                aria-label=\"Yes\"\n                value=\"yes\"\n        >\n            <span class=\"was-this-helpful__button-text fl-text-bold\">Yes<\/span>\n            <i class=\"was-this-helpful__button-icon\">\n                <svg width=\"22\" height=\"22\" viewBox=\"0 0 22 22\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                    <g id=\"thumbs-up\" clip-path=\"url(#clip0_604_3418)\">\n            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While less-severe side effects such as diarrhea and increased risk of bone fractures are prominently listed on the Food and Drug Administration&#8217;s (FDA&#8217;s) medication guide for Nexium, lawsuits allege that drugmaker AstraZeneca failed to warn physicians and users about the drug&#8217;s more serious risks. In addition to Nexium, other brand names in the class of drugs called proton pump inhibitors (PPIs) that also have been blamed for these injuries include Prilosec and Prevacid.<\/p>\n","protected":false},"author":41135,"featured_media":0,"parent":353191,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"app\/Http\/Controllers\/Templates\/ArticleWithBreadcrumbsController.php","meta":{"_acf_changed":false,"_stopmodifiedupdate":true,"_modified_date":"","_autodraft_ids":[],"_cloudinary_featured_overwrite":false,"_sb_is_suggestion_mode":false,"_sb_show_suggestion_boards":false,"_sb_show_comment_boards":false,"_sb_suggestion_history":"","_sb_update_block_changes":"","_is_real_time_mode":false,"_realtime_collaborators":"","footnotes":"","cf_checklist_status":[]},"categories":[2734],"tags":[],"state_laws_tags":[],"flmsa":[],"class_list":["post-353336","page","type-page","status-publish","hentry","category-injury"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/pages\/353336","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/users\/41135"}],"replies":[{"embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/comments?post=353336"}],"version-history":[{"count":0,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/pages\/353336\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/pages\/353191"}],"wp:attachment":[{"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/media?parent=353336"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/categories?post=353336"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/tags?post=353336"},{"taxonomy":"state_laws_tags","embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/state_laws_tags?post=353336"},{"taxonomy":"flmsa","embeddable":true,"href":"https:\/\/www.findlaw.com\/law-api\/wp-json\/wp\/v2\/flmsa?post=353336"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}